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Analytical Testing

Expansive analytical laboratories.

Metrics Contract Services boasts 28,000 square feet of cGMP laboratory space with four analytical labs to support your project, plus dedicated labs featuring state-of-the-art equipment for:

  • Stability studies and storage
  • Microbiology
  • Raw materials testing
  • Trace metals testing
  • Quality control testing
  • Potent and cytotoxic testing and development

Click below image for a detailed  layout of the analytical facilities in our building.

Stability Storage Facilities

Our cGMP facility accommodates a wide range of both reach-in and walk-in chambers for your stability testing program. All of our reach-in and walk-in chambers meet ICH and other global storage conditions standards.

Metrics Contract Services offers ICH-compliant stability storage temperatures from -80°C to 60°C and, where applicable, humidity control from < 25% RH to 75% RH with many intermediate options available. The following conditions are available:

  • -80°C
  • -20°C
  • 5°C
  • 25°C/60% RH
  • 30ºC/65%RH
  • 30ºC/75%RH
  • -40°C<25% RH
  • 40°C/75% RH
  • 50°C
  • 60°C
  • Photostability (ICH Light Conditions)

Our state-of-the-art chambers are equipped with overlapping backup systems, complete with alarms, automated notification and full protection from weather-related concerns. All stability chambers are monitored by a building management system that records temperature and humidity every five minutes and notifies appropriate personnel if pre-determined alarm criteria are met.

The right equipment. The right choice.

With analytical services as the backbone of our company, Metrics Contract Services offers a robust inventory of equipment, enabling us to meet important timelines. Current analytical testing equipment includes: 


  • ~100 HPLC systems (Agilent 1100-1200 series, Shimadzu LC-2010 CHT, Waters 2695, and Hitachi 7000); HPIC systems (Dionex ICS-5000 and 2500); UPLC systems (Waters Acquity H-Class, Shimadzu Prominence UFLC)
  • Services include refractive index, UV, fluorescence, ELSD, CAD, conductivity, amperometry, and diode-array detection
  • LC/MS Agilent 6530 Accurate Mass Q-TOF, Equipped with Jet Stream Focusing, ESI and APCI for MS and MS/MS Analyses
  • GC/MS Agilent 6890 with 5975 MSD, Agilent 7890 with 5977 MSD
  • 10 GC systems (Perkin Elmer Clarus and Agilent 6890 and 7890’s)
  • Services include capillary and packed column, static headspace, direct injection, FID, TCD, and MS
  • 5 UV/VIS Spectrophotometers
  • Dissolution Baths (USP Apparatus I, II, III, and Intrinsic Dissolution)
  • 32 Manual sampling
  • 8 Automated sampling 

Other Analytical Equipment/Services

  • TLC (with photo documentation)
  • FTIR, Near-IR
  • Titrations (colorimetric and potentiometric)
  • pH
  • Karl Fischer (oven, homogenizing, blending volumetric, and coulometric)
  • Atomic Absorption (AA) — Flame, Graphite Furnace, and Cold Vapor
  • Atomic Emission (AE)
  • Inductively Coupled Plasma (ICP/MS and ICP/OES)
  • Viscometer, Polarimeter, Refractometer, Osmometer, Fluorometer
  • TOC
  • Laser Diffraction Particle Size (Malvern Mastersizer 3000 and Mastersizer S)
  • Dynamic Light Scattering (Malvern Zetasizer Nano S)
  • Air Jet Sieve (Hosokawa)
  • TGA-Thermogravimetric Analysis (TA Instruments)
  • DSC-Differential Scanning Calorimetry (TA Instruments)
  • Olympus Polarized Microscope with Digital Camera
  • Melting Range
  • Disintegration Apparatus (Agilent 100)

Microbiological Equipment/Services

  • Sterility Testing (Millipore Steritest Equinox) per USP <71>
  • Bacterial Endotoxin Testing (Pyros Kinetix Turbidimetric System and Gel-Clot) per USP <85>
  • Particulate Matter (Light Obscuration (HIAC) and Optical Microscopy) per USP <788> & <799>
  • Water Testing (Milliflex Pump System)
  • Microbial Enumeration Tests and Tests for Specified Microorganisms per Harmonised USP <61> & <62>
  • Antimicrobial Effectiveness per USP <51>
  • Antibiotic Assay (Cylinder Plate Analysis) per USP <81>
  • Water Activity Testing (AquaLab 4TEV)